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Spectroscopic Identification of Heme Axial Ligands in HtsA that are Involved in Heme Acquisition by Streptococcus pyogenes

The heme-binding proteins Shp and HtsA of Streptococcus pyogenes are part of the heme acquisition machinery in which Shp directly transfers its heme to HtsA. Mutagenesis and spectroscopic analyses were performed to identify the heme axial ligands in HtsA and to characterize axial mutants of HtsA. Re...

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Detalles Bibliográficos
Main Authors: Ran, Yanchao, Liu, Mengyao, Zhu, Hui, Nygaard, Tyler K., Brown, Doreen E., Fabian, Marian, Dooley, David M., Lei, Benfang
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849308/
https://ncbi.nlm.nih.gov/pubmed/20180543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901987h
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