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The Mechanism of Direct Heme Transfer from the Streptococcal Cell Surface Protein Shp to HtsA of the HtsABC Transporter*

The heme-binding proteins Shp and HtsA are part of the heme acquisition machinery found in Streptococcus pyogenes. The hexacoordinate heme (Fe(II)-protoporphyrin IX) or hemochrome form of holoShp (hemoShp) is stable in air in Tris-HCl buffer, pH 8.0, binds to apoHtsA with a K(d) of 120 ± 18 μM and t...

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Hlavní autoři: Nygaard, Tyler K., Blouin, George C., Liu, Mengyao, Fukumura, Maki, Olson, John S., Fabian, Marian, Dooley, David M., Lei, Benfang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423311/
https://ncbi.nlm.nih.gov/pubmed/16717094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M601832200
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