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CARM1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor α by cAMP
The estrogen receptor α (ERα) is activated as a transcription factor by both estrogen and a large variety of other extracellular signals. The mechanisms of this ligand-independent activation, notably by cAMP signaling, are still largely unknown. We now close the gap in the signaling pathway between...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849127/ https://ncbi.nlm.nih.gov/pubmed/20360387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.568410 |
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