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Tamoxifen inhibits acidification in cells independent of the estrogen receptor

Tamoxifen has been reported to have numerous physiological effects that are independent of the estrogen receptor, including sensitization of resistant tumor cells to many chemotherapeutic agents. Drug-resistant cells sequester weak base chemotherapeutics in acidic organelles away from their sites of...

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Detalhes bibliográficos
Main Authors: Altan, Nihal, Chen, Yu, Schindler, Melvin, Simon, Sanford M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16349/
https://ncbi.nlm.nih.gov/pubmed/10200279
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