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Tamoxifen inhibits acidification in cells independent of the estrogen receptor

Tamoxifen has been reported to have numerous physiological effects that are independent of the estrogen receptor, including sensitization of resistant tumor cells to many chemotherapeutic agents. Drug-resistant cells sequester weak base chemotherapeutics in acidic organelles away from their sites of...

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Библиографические подробности
Главные авторы: Altan, Nihal, Chen, Yu, Schindler, Melvin, Simon, Sanford M.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1999
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC16349/
https://ncbi.nlm.nih.gov/pubmed/10200279
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