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The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

The transcriptional program orchestrated by Hedgehog signaling depends on the Gli family of transcription factors. Gli proteins can be converted to either transcriptional activators or truncated transcriptional repressors. We show that the interaction between Gli3 and Suppressor of Fused (Sufu) regu...

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Autores principales: Humke, Eric W., Dorn, Karolin V., Milenkovic, Ljiljana, Scott, Matthew P., Rohatgi, Rajat
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849124/
https://ncbi.nlm.nih.gov/pubmed/20360384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1902910
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