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Specific Targeting to B Cells by Lipid-Based Nanoparticles Conjugated with a Novel CD22- ScFv
The CD22 antigen is a viable target for therapeutic intervention for B-cell lymphomas. Several therapeutic anti-CD22 antibodies as well as an anti-CD22-based immunotoxin (HA22) are currently under investigation in clinical settings. Coupling of anti-CD22 reagents with a nano-drug delivery vehicle is...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849008/ https://ncbi.nlm.nih.gov/pubmed/20122924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2010.01.006 |
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