Hyperthermia-triggered intracellular delivery of anticancer agent to HER2(+) cells by HER2-specific Affibody (ZHER2-GS-Cys)-Conjugated Thermosensitive Liposomes (HER2(+) Affisomes)

We previously reported the formulation and physical properties of HER2 (Human Epidermal Growth Factor Receptor 2)-specific Affibody (ZHER2:342-Cys) conjugated thermosensitive liposomes (HER2(+) Affisomes). Here we examined localized delivery potential of these Affisomes by monitoring cellular intera...

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Detalhes bibliográficos
Main Authors: Smith, Brandon, Lyakhov, Ilya, Loomis, Kristin, Needle, Danielle, Baxa, Ulrich, Yavlovich, Amichai, Capala, Jacek, Blumenthal, Robert, Puri, Anu
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136211/
https://ncbi.nlm.nih.gov/pubmed/21501640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.04.005
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