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A NADPH oxidase dependent redox signaling pathway mediates the selective radiosensitization effect of parthenolide in prostate cancer cells

Cancer cells are usually under higher oxidative stress than normal cells are. We hypothesize that introducing additional ROS insults or suppressing antioxidant capacity may selectively enhance cancer cell killing by oxidative-stress generating agents through stress overload or stress sensitization,...

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Détails bibliographiques
Auteurs principaux: Sun, Yulan, Clair, Daret K., Xu, Yong, Crooks, Peter A., Clair, William H.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848907/
https://ncbi.nlm.nih.gov/pubmed/20233868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4572
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