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Diet-Induced Obesity Alters Vincristine Pharmacokinetics in Blood and Tissues of Mice
Obesity is associated with poorer outcome from many cancers, including leukemia. One possible contributor to this could be suboptimal chemotherapy dosing in obese patients. We have previously found that vincristine (VCR) is less effective in obese compared to non-obese mice with leukemia, despite we...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848885/ https://ncbi.nlm.nih.gov/pubmed/20083201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2010.01.007 |
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