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Roles of Coactivators in Hypoxic Induction of the Erythropoietin Gene
BACKGROUND: Hypoxia-inducible expression of the erythropoietin (EPO) gene is mediated principally by hypoxia-inducible factor 2α (HIF-2α) in Hep3B cells under physiologic conditions. How/whether p300/CBP and the members of p160 coactivator family potentiate hypoxic induction of endogenous EPO and ot...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848849/ https://ncbi.nlm.nih.gov/pubmed/20368990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010002 |
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