Roles of Coactivators in Hypoxic Induction of the Erythropoietin Gene

BACKGROUND: Hypoxia-inducible expression of the erythropoietin (EPO) gene is mediated principally by hypoxia-inducible factor 2α (HIF-2α) in Hep3B cells under physiologic conditions. How/whether p300/CBP and the members of p160 coactivator family potentiate hypoxic induction of endogenous EPO and ot...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Feng, Zhang, Ruixue, Wu, Xiaomeng, Hankinson, Oliver
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848849/
https://ncbi.nlm.nih.gov/pubmed/20368990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010002
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