General Anesthetics Inhibit Erythropoietin Induction under Hypoxic Conditions in the Mouse Brain

BACKGROUND: Erythropoietin (EPO), originally identified as a hematopoietic growth factor produced in the kidney and fetal liver, is also endogenously expressed in the central nervous system (CNS). EPO in the CNS, mainly produced in astrocytes, is induced under hypoxic conditions in a hypoxia-inducib...

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Bibliographic Details
Main Authors: Tanaka, Tomoharu, Kai, Shinichi, Koyama, Tomohiro, Daijo, Hiroki, Adachi, Takehiko, Fukuda, Kazuhiko, Hirota, Kiichi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246473/
https://ncbi.nlm.nih.gov/pubmed/22216265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029378
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