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General Anesthetics Inhibit Erythropoietin Induction under Hypoxic Conditions in the Mouse Brain

BACKGROUND: Erythropoietin (EPO), originally identified as a hematopoietic growth factor produced in the kidney and fetal liver, is also endogenously expressed in the central nervous system (CNS). EPO in the CNS, mainly produced in astrocytes, is induced under hypoxic conditions in a hypoxia-inducib...

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Detalhes bibliográficos
Main Authors: Tanaka, Tomoharu, Kai, Shinichi, Koyama, Tomohiro, Daijo, Hiroki, Adachi, Takehiko, Fukuda, Kazuhiko, Hirota, Kiichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246473/
https://ncbi.nlm.nih.gov/pubmed/22216265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029378
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