Differential changes of glutathione levels in astrocytes and neurons in ischemic brains by two-photon imaging

Using two-photon imaging techniques with monochlorobimane as a glutathione (GSH) probe, we investigated GSH levels in both core and penumbra regions of an ischemic brain after middle cerebral artery occlusion. We found that the GSH level significantly decreased in the ischemic core, but increased si...

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Detalhes bibliográficos
Principais autores: Bragin, Denis E, Zhou, Bo, Ramamoorthy, Prabhu, Müller, Wolfgang S, Connor, John A, Shi, Honglian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848708/
https://ncbi.nlm.nih.gov/pubmed/20104233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.9
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