Neuron-Derived Estrogen Is Critical for Astrocyte Activation and Neuroprotection of the Ischemic Brain

17β-Estradiol (E2) is produced from androgens via the action of the enzyme aromatase. E2 is known to be made in neurons in the brain, but the functions of neuron-derived E2 in the ischemic brain are unclear. Here, we used a forebrain neuron-specific aromatase KO (FBN-ARO-KO) mouse model to deplete n...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Neurosci
Главные авторы: Lu, Yujiao, Sareddy, Gangadhara R., Wang, Jing, Zhang, Quanguang, Tang, Fu-Lei, Pratap, Uday P., Tekmal, Rajeshwar R., Vadlamudi, Ratna K., Brann, Darrell W.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2020
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534920/
https://ncbi.nlm.nih.gov/pubmed/32817249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0115-20.2020
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы