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HSPG-Binding Peptide Corresponding to the Exon 6a-Encoded Domain of VEGF Inhibits Tumor Growth by Blocking Angiogenesis in Murine Model

Vascular endothelial growth factor VEGF(165) is a critical element for development of the vascular system in physiological and pathological angiogenesis. VEGF isoforms have different affinities for heparan sulphate proteoglycan (HSPG) as well as for VEGF receptors; HSPGs are important regulators in...

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Detalhes bibliográficos
Main Authors: Lee, Tong-Young, Folkman, Judah, Javaherian, Kashi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848586/
https://ncbi.nlm.nih.gov/pubmed/20376344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009945
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