Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis
Vascular endothelial growth factor (VEGF) binding to the kinase domain receptor (KDR/FLK1 or VEGFR–2) mediates vascularization and tumor-induced angiogenesis. Since there is evidence that KDR plays an important role in tumor angiogenesis, we sought to identify peptides able to block the VEGF–KDR int...
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| 發表在: | EMBO J |
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| Principais autores: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2000
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310222/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10747021/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.7.1525 |
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