Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations

The recent success of genome-wide association studies (GWAS) is now followed by the challenge to determine how the reported susceptibility variants mediate complex traits and diseases. Expression quantitative trait loci (eQTLs) have been implicated in disease associations through overlaps between eQ...

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Detalhes bibliográficos
Main Authors: Nica, Alexandra C., Montgomery, Stephen B., Dimas, Antigone S., Stranger, Barbara E., Beazley, Claude, Barroso, Inês, Dermitzakis, Emmanouil T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848550/
https://ncbi.nlm.nih.gov/pubmed/20369022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000895
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