Modifier Effects between Regulatory and Protein-Coding Variation

Genome-wide associations have shown a lot of promise in dissecting the genetics of complex traits in humans with single variants, yet a large fraction of the genetic effects is still unaccounted for. Analyzing genetic interactions between variants (epistasis) is one of the potential ways forward. We...

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Hauptverfasser: Dimas, Antigone S., Stranger, Barbara E., Beazley, Claude, Finn, Robert D., Ingle, Catherine E., Forrest, Matthew S., Ritchie, Matthew E., Deloukas, Panos, Tavaré, Simon, Dermitzakis, Emmanouil T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570624/
https://ncbi.nlm.nih.gov/pubmed/18974877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000244
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