Modifier Effects between Regulatory and Protein-Coding Variation

Genome-wide associations have shown a lot of promise in dissecting the genetics of complex traits in humans with single variants, yet a large fraction of the genetic effects is still unaccounted for. Analyzing genetic interactions between variants (epistasis) is one of the potential ways forward. We...

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Bibliografiska uppgifter
Huvudupphovsmän: Dimas, Antigone S., Stranger, Barbara E., Beazley, Claude, Finn, Robert D., Ingle, Catherine E., Forrest, Matthew S., Ritchie, Matthew E., Deloukas, Panos, Tavaré, Simon, Dermitzakis, Emmanouil T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2008
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570624/
https://ncbi.nlm.nih.gov/pubmed/18974877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000244
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