Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations

The recent success of genome-wide association studies (GWAS) is now followed by the challenge to determine how the reported susceptibility variants mediate complex traits and diseases. Expression quantitative trait loci (eQTLs) have been implicated in disease associations through overlaps between eQ...

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Autores principales: Nica, Alexandra C., Montgomery, Stephen B., Dimas, Antigone S., Stranger, Barbara E., Beazley, Claude, Barroso, Inês, Dermitzakis, Emmanouil T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848550/
https://ncbi.nlm.nih.gov/pubmed/20369022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000895
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