Transient Receptor Potential Vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice

BACKGROUND: Cisplatin is primarily used for treatment of ovarian and testicular cancer. Oxaliplatin is the only effective treatment for metastatic colorectal cancer. Both are known to cause dose related, cumulative toxic effects on the peripheral nervous system and thirty to forty percent of cancer...

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Autori principali: Ta, Lauren E, Bieber, Allan J, Carlton, Susan M, Loprinzi, Charles L, Low, Philip A, Windebank, Anthony J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848188/
https://ncbi.nlm.nih.gov/pubmed/20205720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-15
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