Transient Receptor Potential Vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice

BACKGROUND: Cisplatin is primarily used for treatment of ovarian and testicular cancer. Oxaliplatin is the only effective treatment for metastatic colorectal cancer. Both are known to cause dose related, cumulative toxic effects on the peripheral nervous system and thirty to forty percent of cancer...

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Détails bibliographiques
Auteurs principaux: Ta, Lauren E, Bieber, Allan J, Carlton, Susan M, Loprinzi, Charles L, Low, Philip A, Windebank, Anthony J
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848188/
https://ncbi.nlm.nih.gov/pubmed/20205720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-15
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