A Novel and Selective Poly (ADP-Ribose) Polymerase Inhibitor Ameliorates Chemotherapy-Induced Painful Neuropathy

BACKGROUND: Chemotherapy-induced neuropathy is the principle dose limiting factor requiring discontinuation of many chemotherapeutic agents, including cisplatin and oxaliplatin. About 30 to 40% of patients receiving chemotherapy develop pain and sensory changes. Given that poly (ADP-ribose) polymera...

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Detalhes bibliográficos
Main Authors: Ta, Lauren E., Schmelzer, James D., Bieber, Allan J., Loprinzi, Charles L., Sieck, Gary C., Brederson, Jill D., Low, Philip A., Windebank, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542321/
https://ncbi.nlm.nih.gov/pubmed/23326593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054161
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