Engraftment, Differentiation and Functional Benefits of Autologous Cardiosphere-Derived Cells in Porcine Ischemic Cardiomyopathy

BACKGROUND: Cardiosphere-derived cells (CDCs) isolated from human endomyocardial biopsies reduce infarct size and improve cardiac function in mice. Safety and efficacy testing in large animals is necessary for clinical translation. METHODS AND RESULTS: Mesenchymal stem cells, which resemble CDCs in...

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Autors principals: Johnston, Peter V., Sasano, Tetsuo, Mills, Kevin, Evers, Robert, Lee, Shuo-Tsan, Smith, Rachel Ruckdeschel, Lardo, Albert C., Lai, Shenghan, Steenbergen, Charles, Gerstenblith, Gary, Lange, Richard, Marbán, Eduardo
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848167/
https://ncbi.nlm.nih.gov/pubmed/19738142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.816058
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