Engraftment, Differentiation and Functional Benefits of Autologous Cardiosphere-Derived Cells in Porcine Ischemic Cardiomyopathy

BACKGROUND: Cardiosphere-derived cells (CDCs) isolated from human endomyocardial biopsies reduce infarct size and improve cardiac function in mice. Safety and efficacy testing in large animals is necessary for clinical translation. METHODS AND RESULTS: Mesenchymal stem cells, which resemble CDCs in...

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Main Authors: Johnston, Peter V., Sasano, Tetsuo, Mills, Kevin, Evers, Robert, Lee, Shuo-Tsan, Smith, Rachel Ruckdeschel, Lardo, Albert C., Lai, Shenghan, Steenbergen, Charles, Gerstenblith, Gary, Lange, Richard, Marbán, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848167/
https://ncbi.nlm.nih.gov/pubmed/19738142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.816058
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