Engraftment, Differentiation and Functional Benefits of Autologous Cardiosphere-Derived Cells in Porcine Ischemic Cardiomyopathy

BACKGROUND: Cardiosphere-derived cells (CDCs) isolated from human endomyocardial biopsies reduce infarct size and improve cardiac function in mice. Safety and efficacy testing in large animals is necessary for clinical translation. METHODS AND RESULTS: Mesenchymal stem cells, which resemble CDCs in...

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Bibliografiske detaljer
Main Authors: Johnston, Peter V., Sasano, Tetsuo, Mills, Kevin, Evers, Robert, Lee, Shuo-Tsan, Smith, Rachel Ruckdeschel, Lardo, Albert C., Lai, Shenghan, Steenbergen, Charles, Gerstenblith, Gary, Lange, Richard, Marbán, Eduardo
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848167/
https://ncbi.nlm.nih.gov/pubmed/19738142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.816058
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