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Two Phases of Actin Polymerization Display Different Dependencies on PI(3,4,5)P(3) Accumulation and Have Unique Roles during Chemotaxis
The directional movement of cells in chemoattractant gradients requires sophisticated control of the actin cytoskeleton. Uniform exposure of Dictyostelium discoideum amoebae as well as mammalian leukocytes to chemoattractant triggers two phases of actin polymerization. In the initial rapid phase, mo...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC284804/ https://ncbi.nlm.nih.gov/pubmed/14595116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-05-0339 |
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