Two Phases of Actin Polymerization Display Different Dependencies on PI(3,4,5)P(3) Accumulation and Have Unique Roles during Chemotaxis

The directional movement of cells in chemoattractant gradients requires sophisticated control of the actin cytoskeleton. Uniform exposure of Dictyostelium discoideum amoebae as well as mammalian leukocytes to chemoattractant triggers two phases of actin polymerization. In the initial rapid phase, mo...

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Detalles Bibliográficos

Publicado en:	Mol Biol Cell
Autores principales:	Chen, Lingfeng, Janetopoulos, Chris, Huang, Yi Elaine, Iijima, Miho, Borleis, Jane, Devreotes, Peter N.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Cell Biology 2003
Materias:	Articles
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284804/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14595116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-05-0339
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