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The Simultaneous Production of Phosphatidic Acid and Diacylglycerol Is Essential for the Translocation of Protein Kinase Cε to the Plasma Membrane in RBL-2H3 Cells
To evaluate the role of the C2 domain in protein kinase Cε (PKCε) localization and activation after stimulation of the IgE receptor in RBL-2H3 cells, we used a series of mutants located in the phospholipid binding region of the enzyme. The results obtained suggest that the interaction of the C2 doma...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC284792/ https://ncbi.nlm.nih.gov/pubmed/12960426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-05-0295 |
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