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The Simultaneous Production of Phosphatidic Acid and Diacylglycerol Is Essential for the Translocation of Protein Kinase Cε to the Plasma Membrane in RBL-2H3 Cells

To evaluate the role of the C2 domain in protein kinase Cε (PKCε) localization and activation after stimulation of the IgE receptor in RBL-2H3 cells, we used a series of mutants located in the phospholipid binding region of the enzyme. The results obtained suggest that the interaction of the C2 doma...

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書誌詳細
主要な著者: Jose Lopez-Andreo, Maria, Gomez-Fernandez, Juan C., Corbalan-Garcia, Senena
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC284792/
https://ncbi.nlm.nih.gov/pubmed/12960426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-05-0295
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