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β-secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins

The amyloid precursor family of proteins are of considerable interest both because of their role in Alzheimer’s disease pathogenesis and because of their normal physiological functions. In mammals, the amyloid precursor protein (APP) has two homologs, amyloid precursor-like protein 1 and amyloid pre...

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Detaylı Bibliyografya
Asıl Yazarlar: Frigerio, Carlo Sala, Fadeeva, Julia V., Minogue, Aedín M., Citron, Martin, Leuven, Fred Van, Stufenbiel, Matthias, Paganetti, Paolo, Selkoe, Dennis J., Walsh, Dominic M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847843/
https://ncbi.nlm.nih.gov/pubmed/20163459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07579.x
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