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β-secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins
The amyloid precursor family of proteins are of considerable interest both because of their role in Alzheimer’s disease pathogenesis and because of their normal physiological functions. In mammals, the amyloid precursor protein (APP) has two homologs, amyloid precursor-like protein 1 and amyloid pre...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847843/ https://ncbi.nlm.nih.gov/pubmed/20163459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07579.x |
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