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Differentiation-Induced Uroplakin III Expression Promotes Urothelial Cell Death in Response to Uropathogenic E. coli
Uropathogenic E. coli (UPEC) expressing type 1 pili underlie most urinary tract infections (UTIs). UPEC adherence to the bladder urothelium induces a rapid apoptosis and exfoliation of terminally-differentiated urothelial cells, a critical event in pathogenesis. Of the four major uroplakin proteins...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847841/ https://ncbi.nlm.nih.gov/pubmed/19007907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2008.10.008 |
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