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Differentiation-Induced Uroplakin III Expression Promotes Urothelial Cell Death in Response to Uropathogenic E. coli

Uropathogenic E. coli (UPEC) expressing type 1 pili underlie most urinary tract infections (UTIs). UPEC adherence to the bladder urothelium induces a rapid apoptosis and exfoliation of terminally-differentiated urothelial cells, a critical event in pathogenesis. Of the four major uroplakin proteins...

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Bibliografske podrobnosti
Main Authors: Thumbikat, Praveen, Berry, Ruth E., Schaeffer, Anthony J., Klumpp, David J.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847841/
https://ncbi.nlm.nih.gov/pubmed/19007907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2008.10.008
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