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Uropathogenic Escherichia coli Induces Extrinsic and Intrinsic Cascades To Initiate Urothelial Apoptosis

A murine model of urinary tract infection identified urothelial apoptosis as a key event in the pathogenesis mediated by uropathogenic Escherichia coli (UPEC), yet the mechanism of this important host response is not well characterized. We employed a culture model of UPEC-urothelium interactions to...

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Detalhes bibliográficos
Main Authors: Klumpp, David J., Rycyk, Matthew T., Chen, Michael C., Thumbikat, Praveen, Sengupta, Shomit, Schaeffer, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594819/
https://ncbi.nlm.nih.gov/pubmed/16926402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00376-06
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