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Multi-locus models of genetic risk of disease

BACKGROUND: Evidence for genetic contribution to complex diseases is described by recurrence risks to relatives of diseased individuals. Genome-wide association studies allow a description of the genetics of the same diseases in terms of risk loci, their effects and allele frequencies. To reconcile...

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Bibliografiske detaljer
Main Authors: Wray, Naomi R, Goddard, Michael E
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847701/
https://ncbi.nlm.nih.gov/pubmed/20181060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm131
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