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Characterization of Active Site Residues of Nitroalkane Oxidase

The flavoenzyme nitroalkane oxidase catalyzes the oxidation of primary and secondary nitrolkanes to the corresponding aldehydes and ketones plus nitrite. The structure of the enzyme shows that Serl71 forms a hydrogen bond to the flavin N5, suggesting that it plays a role in catalysis. Cys397 and Tyr...

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Autors principals: Valley, Michael P., Fenny, Nana S., Ali, Shah R., Fitzpatrick, Paul F.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847678/
https://ncbi.nlm.nih.gov/pubmed/20056514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2009.12.004
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