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The Na(+)/H(+) Exchanger NHE6 in the Endosomal Recycling System Is Involved in the Development of Apical Bile Canalicular Surface Domains in HepG2 Cells

Polarized epithelial cells develop and maintain distinct apical and basolateral surface domains despite a continuous flux of membranes between these domains. The Na(+)/H(+)exchanger NHE6 localizes to endosomes but its function is unknown. Here, we demonstrate that polarized hepatoma HepG2 cells expr...

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Detalhes bibliográficos
Main Authors: Ohgaki, Ryuichi, Matsushita, Masafumi, Kanazawa, Hiroshi, Ogihara, Satoshi, Hoekstra, Dick, van IJzendoorn, Sven C.D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847532/
https://ncbi.nlm.nih.gov/pubmed/20130086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-09-0767
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