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The Na(+)/H(+) Exchanger NHE6 in the Endosomal Recycling System Is Involved in the Development of Apical Bile Canalicular Surface Domains in HepG2 Cells

Polarized epithelial cells develop and maintain distinct apical and basolateral surface domains despite a continuous flux of membranes between these domains. The Na(+)/H(+)exchanger NHE6 localizes to endosomes but its function is unknown. Here, we demonstrate that polarized hepatoma HepG2 cells expr...

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Bibliographic Details
Main Authors: Ohgaki, Ryuichi, Matsushita, Masafumi, Kanazawa, Hiroshi, Ogihara, Satoshi, Hoekstra, Dick, van IJzendoorn, Sven C.D.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847532/
https://ncbi.nlm.nih.gov/pubmed/20130086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-09-0767
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