Comparison of rates of intracellular metabolism of zidovudine in human and primate peripheral blood mononuclear cells.
3'-Azido-3'-deoxythymidine (AZT) is a drug of choice for the treatment of AIDS. On the basis of pharmacokinetic data, the nonhuman primate Macaca nemestrina has been shown to be a suitable animal model for use in the study of the disposition of AZT. However, since AZT is activated to its metabolite,...
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| Published in: | Antimicrob Agents Chemother |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1994
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7840577/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.10.2398 |
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