Possible intermolecular interaction between quinolones and biphenylacetic acid inhibits gamma-aminobutyric acid receptor sites.

The combination of some new quinolone antibacterial agents with 4-biphenylacetic acid (BPAA), a metabolite of fenbufen, is known to specifically induce functional blockade of the gamma-aminobutyric acid (GABA) receptors. The mechanisms of these drug interactions were further examined. Scatchard anal...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Akahane, K, Kimura, Y, Tsutomi, Y, Hayakawa, I
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284738/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7840564/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.10.2323
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