Inhibitory effects of quinolone antibacterial agents on gamma-aminobutyric acid binding to receptor sites in rat brain membranes.

The specific binding of 3H-labeled gamma-aminobutyric acid ([3H]GABA) to synaptic plasma membranes from rat brains was inhibited by various quinolonecarboxylic acid derivatives (quinolones), and these inhibitions were concentration dependent. The binding of [3H]muscimol to GABAA sites was also inhib...

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Hlavní autoři: Tsuji, A, Sato, H, Kume, Y, Tamai, I, Okezaki, E, Nagata, O, Kato, H
Médium: Artigo
Jazyk:Inglês
Vydáno: 1988
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC172133/
https://ncbi.nlm.nih.gov/pubmed/2834994
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