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The role of NOTCH1 signaling in T-ALL
The identification of activating mutations in NOTCH1 in over 50% of T-cell acute lymphoblastic leukemias (T-ALL) has generated major interest in the elucidation of the mechanisms of transformation downstream of oncogenic NOTCH and in the targeting of the NOTCH signaling pathway in this disease. Smal...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847371/ https://ncbi.nlm.nih.gov/pubmed/20008221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/asheducation-2009.1.353 |
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