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CD8 T Cell Recall Responses Are Regulated by the Tissue Tropism of the Memory Cell and Pathogen
Whether memory CD8 T cells can be reactivated in nonlymphoid tissues is unclear. Using mice lacking the spleen, lymph nodes, or both, we show that the secondary T cell response, but not homeostatic maintenance of memory cells, required lymphoid tissue. Whereas primary and secondary CD8 T cell respon...
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Glavni autori: | , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2006
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847276/ https://ncbi.nlm.nih.gov/pubmed/17082587 |
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