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CD8 T Cell Recall Responses Are Regulated by the Tissue Tropism of the Memory Cell and Pathogen

Whether memory CD8 T cells can be reactivated in nonlymphoid tissues is unclear. Using mice lacking the spleen, lymph nodes, or both, we show that the secondary T cell response, but not homeostatic maintenance of memory cells, required lymphoid tissue. Whereas primary and secondary CD8 T cell respon...

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Bibliografski detalji
Glavni autori: Klonowski, Kimberly D., Marzo, Amanda L., Williams, Kristina J., Lee, Seung-Joo, Pham, Quynh-Mai, Lefrançois, Leo
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847276/
https://ncbi.nlm.nih.gov/pubmed/17082587
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