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Fusion of short telomeres in human cells is characterized by extensive deletion and microhomology, and can result in complex rearrangements
Telomere fusion is an important mutational event that has the potential to lead to large-scale genomic rearrangements of the types frequently observed in cancer. We have developed single-molecule approaches to detect, isolate and characterize the DNA sequence of telomere fusion events in human cells...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847243/ https://ncbi.nlm.nih.gov/pubmed/20026586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1183 |
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