PCRPi: Presaging Critical Residues in Protein interfaces, a new computational tool to chart hot spots in protein interfaces

Protein–protein interactions (PPIs) are ubiquitous in Biology, and thus offer an enormous potential for the discovery of novel therapeutics. Although protein interfaces are large and lack defining physiochemical traits, is well established that only a small portion of interface residues, the so-call...

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Bibliographic Details
Main Authors: Assi, Salam A., Tanaka, Tomoyuki, Rabbitts, Terence H., Fernandez-Fuentes, Narcis
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Methods Online
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847225/
https://ncbi.nlm.nih.gov/pubmed/20008102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1158
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