DNA dynamics play a role as a basal transcription factor in the positioning and regulation of gene transcription initiation

We assess the role of DNA breathing dynamics as a determinant of promoter strength and transcription start site (TSS) location. We compare DNA Langevin dynamic profiles of representative gene promoters, calculated with the extended non-linear PBD model of DNA with experimental data on transcription...

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Detalhes bibliográficos
Main Authors: Alexandrov, Boian S., Gelev, Vladimir, Yoo, Sang Wook, Alexandrov, Ludmil B., Fukuyo, Yayoi, Bishop, Alan R., Rasmussen, Kim Ø., Usheva, Anny
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847213/
https://ncbi.nlm.nih.gov/pubmed/20019064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1084
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