A nonlinear dynamic model of DNA with a sequence-dependent stacking term

No simple model exists that accurately describes the melting behavior and breathing dynamics of double-stranded DNA as a function of nucleotide sequence. This is especially true for homogenous and periodic DNA sequences, which exhibit large deviations in melting temperature from predictions made by...

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Main Authors: Alexandrov, Boian S., Gelev, Vladimir, Monisova, Yevgeniya, Alexandrov, Ludmil B., Bishop, Alan R., Rasmussen, Kim Ø., Usheva, Anny
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Computational Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673413/
https://ncbi.nlm.nih.gov/pubmed/19264801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp016
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