Diclofenac-induced Stimulation of SMCT1 (SLC5A8) in a Heterologous Expression System: a RPE specific phenomenon

SMCT1 is a Na(+)-coupled monocarboxylate transporter expressed in a variety of tissues including kidney, thyroid, small intestine, colon, brain and retina. We found recently that several non-steroidal anti-inflammatory drugs (NSAIDs) inhibit the activity of SMCT1. Here we evaluated the effect of dic...

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Bibliografiske detaljer
Main Authors: Ananth, Sudha, Zhuang, Lina, Gopal, Elangovan, Itagaki, Shiro, Ellappan, Babu, Smith, Sylvia B., Ganapathy, Vadivel, Martin, Pamela
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847057/
https://ncbi.nlm.nih.gov/pubmed/20178774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.02.109
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