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A Dynamic Model of HIV Integrase Inhibition and Drug Resistance
Human immunodeficiency virus type 1 (HIV-1) integrase is one of three virally encoded enzymes essential for replication and, therefore, a rational choice as a drug target for the treatment of HIV-1 infected individuals. In 2007 raltegravir became the first integrase inhibitor approved for use in the...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2846753/ https://ncbi.nlm.nih.gov/pubmed/20096702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.033 |
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