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Molecular dynamics studies on the HIV-1 integrase catalytic domain.

The HIV-1 integrase, which is essential for viral replication, catalyzes the insertion of viral DNA into the host chromosome, thereby recruiting host cell machinery into making viral proteins. It represents the third main HIV enzyme target for inhibitor design, the first two being the reverse transc...

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Détails bibliographiques
Auteurs principaux: Lins, R D, Briggs, J M, Straatsma, T P, Carlson, H A, Greenwald, J, Choe, S, McCammon, J A
Format: Artigo
Langue:Inglês
Publié: 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300270/
https://ncbi.nlm.nih.gov/pubmed/10354426
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