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Vacuolar ATPase Regulates Zymogen Activation in Pancreatic Acini
Supramaximal concentrations of cholecystokinin or its analogue caerulein have been shown to stimulate the proteolytic activation of zymogens within the pancreatic acinar cell and initiate acute pancreatitis. Previous studies suggest that a low pH compartment might be required for activation. To test...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2846595/ https://ncbi.nlm.nih.gov/pubmed/15582989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M413513200 |
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